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Clinical Impact of X-Ray Repair Cross-Complementary 1 (XRCC1) and the Immune Environment in Colorectal Adenoma–Carcinoma Pathway Progression

PURPOSE: Colorectal cancer (CRC) can develop via a hypermutagenic pathway characterized by frequent somatic DNA base-pair mutations. Alternatively, the immunogenicity of tumor cells themselves may influence the anticancer activity of the immune effector cells. Impaired DNA repair mechanisms drive mu...

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Detalles Bibliográficos
Autores principales:	Zhang, Yu, Zhang, Xin, Jin, Zhuoyi, Chen, Huiyan, Zhang, Chenjing, Wang, wangyue, Jing, Jiyong, Pan, Wensheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559027/ https://www.ncbi.nlm.nih.gov/pubmed/34737598 http://dx.doi.org/10.2147/JIR.S331010

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