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Organising pneumonia manifesting as a late-phase complication of COVID-19

Acute COVID-19 usually lasts 4 weeks from the onset of symptoms. We report two cases of COVID-19-associated organising pneumonia (OP) occurring beyond 4 weeks from the acute onset of symptoms. Both tested positive for SARS reverse transcription–PCR 2 months before presentation with a resolution of r...

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Autores principales: Ng, Boon Hau, Ban, Andrea Yu-Lin, Nik Abeed, Nik Nuratiqah, Faisal, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559103/
https://www.ncbi.nlm.nih.gov/pubmed/34716149
http://dx.doi.org/10.1136/bcr-2021-246119
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author Ng, Boon Hau
Ban, Andrea Yu-Lin
Nik Abeed, Nik Nuratiqah
Faisal, Mohamed
author_facet Ng, Boon Hau
Ban, Andrea Yu-Lin
Nik Abeed, Nik Nuratiqah
Faisal, Mohamed
author_sort Ng, Boon Hau
collection PubMed
description Acute COVID-19 usually lasts 4 weeks from the onset of symptoms. We report two cases of COVID-19-associated organising pneumonia (OP) occurring beyond 4 weeks from the acute onset of symptoms. Both tested positive for SARS reverse transcription–PCR 2 months before presentation with a resolution of respiratory symptoms. The first case presented with residual fatigue and worsening exertional dyspnoea. Chest CT revealed an OP pattern. The second case presented with worsening cough and new-onset pleuritic chest pain with persistent radiological consolidation. A transbronchial lung biopsy confirmed OP. Both patients responded well to 12 weeks of steroid therapy. This case illustrates the rare presentation of OP as a late sequela of COVID-19 and the good response to steroid therapy.
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spelling pubmed-85591032021-11-04 Organising pneumonia manifesting as a late-phase complication of COVID-19 Ng, Boon Hau Ban, Andrea Yu-Lin Nik Abeed, Nik Nuratiqah Faisal, Mohamed BMJ Case Rep Case Report Acute COVID-19 usually lasts 4 weeks from the onset of symptoms. We report two cases of COVID-19-associated organising pneumonia (OP) occurring beyond 4 weeks from the acute onset of symptoms. Both tested positive for SARS reverse transcription–PCR 2 months before presentation with a resolution of respiratory symptoms. The first case presented with residual fatigue and worsening exertional dyspnoea. Chest CT revealed an OP pattern. The second case presented with worsening cough and new-onset pleuritic chest pain with persistent radiological consolidation. A transbronchial lung biopsy confirmed OP. Both patients responded well to 12 weeks of steroid therapy. This case illustrates the rare presentation of OP as a late sequela of COVID-19 and the good response to steroid therapy. BMJ Publishing Group 2021-10-29 /pmc/articles/PMC8559103/ /pubmed/34716149 http://dx.doi.org/10.1136/bcr-2021-246119 Text en © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.
spellingShingle Case Report
Ng, Boon Hau
Ban, Andrea Yu-Lin
Nik Abeed, Nik Nuratiqah
Faisal, Mohamed
Organising pneumonia manifesting as a late-phase complication of COVID-19
title Organising pneumonia manifesting as a late-phase complication of COVID-19
title_full Organising pneumonia manifesting as a late-phase complication of COVID-19
title_fullStr Organising pneumonia manifesting as a late-phase complication of COVID-19
title_full_unstemmed Organising pneumonia manifesting as a late-phase complication of COVID-19
title_short Organising pneumonia manifesting as a late-phase complication of COVID-19
title_sort organising pneumonia manifesting as a late-phase complication of covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559103/
https://www.ncbi.nlm.nih.gov/pubmed/34716149
http://dx.doi.org/10.1136/bcr-2021-246119
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