Phytochemicals for the treatment of COVID-19

The coronavirus disease 2019 (COVID-19) pandemic has underscored the lack of approved drugs against acute viral diseases. Plants are considered inexhaustible sources of drugs for several diseases and clinical conditions, but plant-derived compounds have seen little success in the field of antivirals...

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Detalles Bibliográficos
Autores principales: Españo, Erica, Kim, Jiyeon, Lee, Kiho, Kim, Jeong-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Microbiological Society of Korea 2021
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559138/
https://www.ncbi.nlm.nih.gov/pubmed/34724178
http://dx.doi.org/10.1007/s12275-021-1467-z
Descripción
Sumario:The coronavirus disease 2019 (COVID-19) pandemic has underscored the lack of approved drugs against acute viral diseases. Plants are considered inexhaustible sources of drugs for several diseases and clinical conditions, but plant-derived compounds have seen little success in the field of antivirals. Here, we present the case for the use of compounds from vascular plants, including alkaloids, flavonoids, polyphenols, and tannins, as antivirals, particularly for the treatment of COVID-19. We review current evidence for the use of these phytochemicals against SARS-CoV-2 infection and present their potential targets in the SARS-CoV-2 replication cycle.

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