Phytochemicals for the treatment of COVID-19

The coronavirus disease 2019 (COVID-19) pandemic has underscored the lack of approved drugs against acute viral diseases. Plants are considered inexhaustible sources of drugs for several diseases and clinical conditions, but plant-derived compounds have seen little success in the field of antivirals...

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Autores principales: Españo, Erica, Kim, Jiyeon, Lee, Kiho, Kim, Jeong-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Microbiological Society of Korea 2021
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559138/
https://www.ncbi.nlm.nih.gov/pubmed/34724178
http://dx.doi.org/10.1007/s12275-021-1467-z
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author Españo, Erica
Kim, Jiyeon
Lee, Kiho
Kim, Jeong-Ki
author_facet Españo, Erica
Kim, Jiyeon
Lee, Kiho
Kim, Jeong-Ki
author_sort Españo, Erica
collection PubMed
description The coronavirus disease 2019 (COVID-19) pandemic has underscored the lack of approved drugs against acute viral diseases. Plants are considered inexhaustible sources of drugs for several diseases and clinical conditions, but plant-derived compounds have seen little success in the field of antivirals. Here, we present the case for the use of compounds from vascular plants, including alkaloids, flavonoids, polyphenols, and tannins, as antivirals, particularly for the treatment of COVID-19. We review current evidence for the use of these phytochemicals against SARS-CoV-2 infection and present their potential targets in the SARS-CoV-2 replication cycle.
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spelling pubmed-85591382021-11-01 Phytochemicals for the treatment of COVID-19 Españo, Erica Kim, Jiyeon Lee, Kiho Kim, Jeong-Ki J Microbiol Minireview The coronavirus disease 2019 (COVID-19) pandemic has underscored the lack of approved drugs against acute viral diseases. Plants are considered inexhaustible sources of drugs for several diseases and clinical conditions, but plant-derived compounds have seen little success in the field of antivirals. Here, we present the case for the use of compounds from vascular plants, including alkaloids, flavonoids, polyphenols, and tannins, as antivirals, particularly for the treatment of COVID-19. We review current evidence for the use of these phytochemicals against SARS-CoV-2 infection and present their potential targets in the SARS-CoV-2 replication cycle. The Microbiological Society of Korea 2021-11-01 2021 /pmc/articles/PMC8559138/ /pubmed/34724178 http://dx.doi.org/10.1007/s12275-021-1467-z Text en © The Microbiological Society of Korea 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Minireview
Españo, Erica
Kim, Jiyeon
Lee, Kiho
Kim, Jeong-Ki
Phytochemicals for the treatment of COVID-19
title Phytochemicals for the treatment of COVID-19
title_full Phytochemicals for the treatment of COVID-19
title_fullStr Phytochemicals for the treatment of COVID-19
title_full_unstemmed Phytochemicals for the treatment of COVID-19
title_short Phytochemicals for the treatment of COVID-19
title_sort phytochemicals for the treatment of covid-19
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559138/
https://www.ncbi.nlm.nih.gov/pubmed/34724178
http://dx.doi.org/10.1007/s12275-021-1467-z
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AT kimjiyeon phytochemicalsforthetreatmentofcovid19
AT leekiho phytochemicalsforthetreatmentofcovid19
AT kimjeongki phytochemicalsforthetreatmentofcovid19

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