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Clone decomposition based on mutation signatures provides novel insights into mutational processes
Intra-tumor heterogeneity is a phenomenon in which mutation profiles differ from cell to cell within the same tumor and is observed in almost all tumors. Understanding intra-tumor heterogeneity is essential from the clinical perspective. Numerous methods have been developed to predict this phenomeno...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559167/ https://www.ncbi.nlm.nih.gov/pubmed/34734181 http://dx.doi.org/10.1093/nargab/lqab093 |