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The clinical implications of sinus tachycardia in mild COVID-19 infection: A retrospective cohort study
OBJECTIVES: This study aims to estimate the prevalence of sinus tachycardia in hospitalized patients with mild COVID-19 infection and to identify the clinical, radiological, and biological characteristics associated with sinus tachycardia. METHODS: A retrospective cohort study was conducted on patie...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559187/ https://www.ncbi.nlm.nih.gov/pubmed/34733514 http://dx.doi.org/10.1177/20503121211054973 |
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author | Hsieh, Jenny Yi Chen Kan, Juliana Yin Li Mattar, Shaikh Abdul Matin Qin, Yan |
author_facet | Hsieh, Jenny Yi Chen Kan, Juliana Yin Li Mattar, Shaikh Abdul Matin Qin, Yan |
author_sort | Hsieh, Jenny Yi Chen |
collection | PubMed |
description | OBJECTIVES: This study aims to estimate the prevalence of sinus tachycardia in hospitalized patients with mild COVID-19 infection and to identify the clinical, radiological, and biological characteristics associated with sinus tachycardia. METHODS: A retrospective cohort study was conducted on patients with mild COVID-19 infection and sinus tachycardia during hospitalization. Outcomes measured included incidences of venous thromboembolism, high-dependency/intensive care unit admission, laboratory parameters, and radiological findings. RESULTS: A total of 236 COVID-19 positive patients admitted to Singapore General Hospital isolation general wards from 1 June 2020 to 30 June 2020 were included in this study. Ninety-seven (41.1%) patients had sinus tachycardia on or during their admission. All patients were monitored in general wards and discharged to community quarantine facilities. None required oxygen support or high-dependency/intensive care unit admission. Sinus tachycardia was associated with increased C-reactive protein level (odds ratio = 1.033, 95% confidence interval = 1.002–1.066), abnormal chest X-ray findings (odds ratio = 3.142, 95% confidence interval = 1.390–7.104), and longer hospitalization (odds ratio = 1.117, 95% confidence interval = 1.010–1.236). There was no significant statistical association between sinus tachycardia and incidences of venous thromboembolism. CONCLUSION: This study suggests that patients with mild COVID-19 infection and concurrent sinus tachycardia are more likely to have higher inflammatory marker levels, abnormal imaging, and prolonged hospitalization. However, no significant association between sinus tachycardia and thromboembolism is identified in mild COVID-19 infection. |
format | Online Article Text |
id | pubmed-8559187 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-85591872021-11-02 The clinical implications of sinus tachycardia in mild COVID-19 infection: A retrospective cohort study Hsieh, Jenny Yi Chen Kan, Juliana Yin Li Mattar, Shaikh Abdul Matin Qin, Yan SAGE Open Med Original Research Article OBJECTIVES: This study aims to estimate the prevalence of sinus tachycardia in hospitalized patients with mild COVID-19 infection and to identify the clinical, radiological, and biological characteristics associated with sinus tachycardia. METHODS: A retrospective cohort study was conducted on patients with mild COVID-19 infection and sinus tachycardia during hospitalization. Outcomes measured included incidences of venous thromboembolism, high-dependency/intensive care unit admission, laboratory parameters, and radiological findings. RESULTS: A total of 236 COVID-19 positive patients admitted to Singapore General Hospital isolation general wards from 1 June 2020 to 30 June 2020 were included in this study. Ninety-seven (41.1%) patients had sinus tachycardia on or during their admission. All patients were monitored in general wards and discharged to community quarantine facilities. None required oxygen support or high-dependency/intensive care unit admission. Sinus tachycardia was associated with increased C-reactive protein level (odds ratio = 1.033, 95% confidence interval = 1.002–1.066), abnormal chest X-ray findings (odds ratio = 3.142, 95% confidence interval = 1.390–7.104), and longer hospitalization (odds ratio = 1.117, 95% confidence interval = 1.010–1.236). There was no significant statistical association between sinus tachycardia and incidences of venous thromboembolism. CONCLUSION: This study suggests that patients with mild COVID-19 infection and concurrent sinus tachycardia are more likely to have higher inflammatory marker levels, abnormal imaging, and prolonged hospitalization. However, no significant association between sinus tachycardia and thromboembolism is identified in mild COVID-19 infection. SAGE Publications 2021-10-29 /pmc/articles/PMC8559187/ /pubmed/34733514 http://dx.doi.org/10.1177/20503121211054973 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Research Article Hsieh, Jenny Yi Chen Kan, Juliana Yin Li Mattar, Shaikh Abdul Matin Qin, Yan The clinical implications of sinus tachycardia in mild COVID-19 infection: A retrospective cohort study |
title | The clinical implications of sinus tachycardia in mild COVID-19 infection: A retrospective cohort study |
title_full | The clinical implications of sinus tachycardia in mild COVID-19 infection: A retrospective cohort study |
title_fullStr | The clinical implications of sinus tachycardia in mild COVID-19 infection: A retrospective cohort study |
title_full_unstemmed | The clinical implications of sinus tachycardia in mild COVID-19 infection: A retrospective cohort study |
title_short | The clinical implications of sinus tachycardia in mild COVID-19 infection: A retrospective cohort study |
title_sort | clinical implications of sinus tachycardia in mild covid-19 infection: a retrospective cohort study |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559187/ https://www.ncbi.nlm.nih.gov/pubmed/34733514 http://dx.doi.org/10.1177/20503121211054973 |
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