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Anti-GD2 IgA kills tumors by neutrophils without antibody-associated pain in the preclinical treatment of high-risk neuroblastoma
BACKGROUND: The addition of monoclonal antibody therapy against GD2 to the treatment of high-risk neuroblastoma led to improved responses in patients. Nevertheless, administration of GD2 antibodies against neuroblastoma is associated with therapy-limiting neuropathic pain. This severe pain is evoked...
Autores principales: | Evers, Mitchell, Stip, Marjolein, Keller, Kaylee, Willemen, Hanneke, Nederend, Maaike, Jansen, Marco, Chan, Chilam, Budding, Kevin, Nierkens, Stefan, Valerius, Thomas, Meyer-Wentrup, Friederike, Eijkelkamp, Niels, Leusen, Jeanette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559241/ https://www.ncbi.nlm.nih.gov/pubmed/34716207 http://dx.doi.org/10.1136/jitc-2021-003163 |
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