Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unprecedented in human history. As a major structural protein, nucleocapsid protein (NPro) is critical to the replication of SARS-CoV-2. In this work, 17 NPro-targeting phenanthridine derivatives were rat...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Ting, Long, Xin-Yan, Ding, Xiao, Fan, Shi-Rui, Cai, Jie-Yun, Yang, Bi-Juan, Zhang, Xin-Fang, Luo, Rong-hua, Yang, Lian, Ruan, Ting, Ren, Juan, Jing, Chen-Xu, Zheng, Yong-Tang, Hao, Xiao-Jiang, Chen, Duo-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559303/
https://www.ncbi.nlm.nih.gov/pubmed/34749200
http://dx.doi.org/10.1016/j.ejmech.2021.113966

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