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Resolution of pituitary microadenoma after coronavirus disease 2019: a case report
BACKGROUND: This report describes the case of a patient whose pituitary microadenoma resolved after he contracted coronavirus disease 2019. To our knowledge, this is one of the first reported cases of pituitary tumor resolution due to viral illness. We present this case to further investigate the re...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559425/ https://www.ncbi.nlm.nih.gov/pubmed/34724974 http://dx.doi.org/10.1186/s13256-021-03127-3 |
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author | Raishan, Salah Alsabri, Mohammed Hanna, Ann Mary Brett, Matthew |
author_facet | Raishan, Salah Alsabri, Mohammed Hanna, Ann Mary Brett, Matthew |
author_sort | Raishan, Salah |
collection | PubMed |
description | BACKGROUND: This report describes the case of a patient whose pituitary microadenoma resolved after he contracted coronavirus disease 2019. To our knowledge, this is one of the first reported cases of pituitary tumor resolution due to viral illness. We present this case to further investigate the relationship between inflammatory response and tumor remission. CASE PRESENTATION: A 32-year-old man in Yemen presented to the hospital with fever, low blood oxygen saturation, and shortness of breath. The patient was diagnosed with coronavirus disease 2019. Past medical history included pituitary microadenoma that was diagnosed using magnetic resonance imaging and secondary adrenal insufficiency, which was treated with steroids. Due to the severity of coronavirus disease 2019, he was treated with steroids and supportive care. Three months after his initial presentation to the hospital, brain magnetic resonance imaging was performed and compared with past scans. Magnetic resonance imaging revealed changes in the microadenoma, including the disappearance of the hypointense lesion and hyperintense enhancement observed on the previous scan. CONCLUSIONS: Pituitary adenomas rarely undergo spontaneous resolution. Therefore, we hypothesized that tumor resolution was secondary to an immune response to coronavirus disease 2019. |
format | Online Article Text |
id | pubmed-8559425 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-85594252021-11-01 Resolution of pituitary microadenoma after coronavirus disease 2019: a case report Raishan, Salah Alsabri, Mohammed Hanna, Ann Mary Brett, Matthew J Med Case Rep Case Report BACKGROUND: This report describes the case of a patient whose pituitary microadenoma resolved after he contracted coronavirus disease 2019. To our knowledge, this is one of the first reported cases of pituitary tumor resolution due to viral illness. We present this case to further investigate the relationship between inflammatory response and tumor remission. CASE PRESENTATION: A 32-year-old man in Yemen presented to the hospital with fever, low blood oxygen saturation, and shortness of breath. The patient was diagnosed with coronavirus disease 2019. Past medical history included pituitary microadenoma that was diagnosed using magnetic resonance imaging and secondary adrenal insufficiency, which was treated with steroids. Due to the severity of coronavirus disease 2019, he was treated with steroids and supportive care. Three months after his initial presentation to the hospital, brain magnetic resonance imaging was performed and compared with past scans. Magnetic resonance imaging revealed changes in the microadenoma, including the disappearance of the hypointense lesion and hyperintense enhancement observed on the previous scan. CONCLUSIONS: Pituitary adenomas rarely undergo spontaneous resolution. Therefore, we hypothesized that tumor resolution was secondary to an immune response to coronavirus disease 2019. BioMed Central 2021-11-01 /pmc/articles/PMC8559425/ /pubmed/34724974 http://dx.doi.org/10.1186/s13256-021-03127-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Raishan, Salah Alsabri, Mohammed Hanna, Ann Mary Brett, Matthew Resolution of pituitary microadenoma after coronavirus disease 2019: a case report |
title | Resolution of pituitary microadenoma after coronavirus disease 2019: a case report |
title_full | Resolution of pituitary microadenoma after coronavirus disease 2019: a case report |
title_fullStr | Resolution of pituitary microadenoma after coronavirus disease 2019: a case report |
title_full_unstemmed | Resolution of pituitary microadenoma after coronavirus disease 2019: a case report |
title_short | Resolution of pituitary microadenoma after coronavirus disease 2019: a case report |
title_sort | resolution of pituitary microadenoma after coronavirus disease 2019: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559425/ https://www.ncbi.nlm.nih.gov/pubmed/34724974 http://dx.doi.org/10.1186/s13256-021-03127-3 |
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