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The nature of the self: Neural analyses and heritability estimates of self‐evaluations in middle childhood
How neural correlates of self‐concept are influenced by environmental versus genetic factors is currently not fully understood. We investigated heritability estimates of behavioral and neural correlates of self‐concept in middle childhood since this phase is an important time window for taking on ne...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559501/ https://www.ncbi.nlm.nih.gov/pubmed/34477265 http://dx.doi.org/10.1002/hbm.25641 |
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author | van Drunen, Lina Dobbelaar, Simone van der Cruijsen, Renske van der Meulen, Mara Achterberg, Michelle Wierenga, Lara M. Crone, Eveline A. |
author_facet | van Drunen, Lina Dobbelaar, Simone van der Cruijsen, Renske van der Meulen, Mara Achterberg, Michelle Wierenga, Lara M. Crone, Eveline A. |
author_sort | van Drunen, Lina |
collection | PubMed |
description | How neural correlates of self‐concept are influenced by environmental versus genetic factors is currently not fully understood. We investigated heritability estimates of behavioral and neural correlates of self‐concept in middle childhood since this phase is an important time window for taking on new social roles in academic and social contexts. To do so, a validated self‐concept fMRI task was applied in a twin sample of 345 participants aged between 7 and 9 years. In the self‐concept condition, participants were asked to indicate whether academic and social traits applied to them whereas the control condition required trait categorization. The self‐processing activation analyses (n = 234) revealed stronger medial prefrontal cortex (mPFC) activation for self than for control conditions. This effect was more pronounced for social‐self than academic self‐traits, whereas stronger dorsolateral prefrontal cortex (DLPFC) activation was observed for academic versus social self‐evaluations. Behavioral genetic modeling (166 complete twin pairs) revealed that 25–52% of the variation in academic self‐evaluations was explained by genetic factors, whereas 16–49% of the variation in social self‐evaluations was explained by shared environmental factors. Neural genetic modeling (91 complete twin pairs) for variation in mPFC and anterior prefrontal cortex (PFC) activation for academic self‐evaluations confirmed genetic and unique environmental influences, whereas anterior PFC activation for social self‐evaluations was additionally influenced by shared environmental influences. This indicates that environmental context possibly has a larger impact on the behavioral and neural correlates of social self‐concept at a young age. This is the first study demonstrating in a young twin sample that self‐concept depends on both genetic and environmental factors, depending on the specific domain. |
format | Online Article Text |
id | pubmed-8559501 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley & Sons, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85595012021-11-08 The nature of the self: Neural analyses and heritability estimates of self‐evaluations in middle childhood van Drunen, Lina Dobbelaar, Simone van der Cruijsen, Renske van der Meulen, Mara Achterberg, Michelle Wierenga, Lara M. Crone, Eveline A. Hum Brain Mapp Research Articles How neural correlates of self‐concept are influenced by environmental versus genetic factors is currently not fully understood. We investigated heritability estimates of behavioral and neural correlates of self‐concept in middle childhood since this phase is an important time window for taking on new social roles in academic and social contexts. To do so, a validated self‐concept fMRI task was applied in a twin sample of 345 participants aged between 7 and 9 years. In the self‐concept condition, participants were asked to indicate whether academic and social traits applied to them whereas the control condition required trait categorization. The self‐processing activation analyses (n = 234) revealed stronger medial prefrontal cortex (mPFC) activation for self than for control conditions. This effect was more pronounced for social‐self than academic self‐traits, whereas stronger dorsolateral prefrontal cortex (DLPFC) activation was observed for academic versus social self‐evaluations. Behavioral genetic modeling (166 complete twin pairs) revealed that 25–52% of the variation in academic self‐evaluations was explained by genetic factors, whereas 16–49% of the variation in social self‐evaluations was explained by shared environmental factors. Neural genetic modeling (91 complete twin pairs) for variation in mPFC and anterior prefrontal cortex (PFC) activation for academic self‐evaluations confirmed genetic and unique environmental influences, whereas anterior PFC activation for social self‐evaluations was additionally influenced by shared environmental influences. This indicates that environmental context possibly has a larger impact on the behavioral and neural correlates of social self‐concept at a young age. This is the first study demonstrating in a young twin sample that self‐concept depends on both genetic and environmental factors, depending on the specific domain. John Wiley & Sons, Inc. 2021-09-03 /pmc/articles/PMC8559501/ /pubmed/34477265 http://dx.doi.org/10.1002/hbm.25641 Text en © 2021 The Authors. Human Brain Mapping published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles van Drunen, Lina Dobbelaar, Simone van der Cruijsen, Renske van der Meulen, Mara Achterberg, Michelle Wierenga, Lara M. Crone, Eveline A. The nature of the self: Neural analyses and heritability estimates of self‐evaluations in middle childhood |
title | The nature of the self: Neural analyses and heritability estimates of self‐evaluations in middle childhood |
title_full | The nature of the self: Neural analyses and heritability estimates of self‐evaluations in middle childhood |
title_fullStr | The nature of the self: Neural analyses and heritability estimates of self‐evaluations in middle childhood |
title_full_unstemmed | The nature of the self: Neural analyses and heritability estimates of self‐evaluations in middle childhood |
title_short | The nature of the self: Neural analyses and heritability estimates of self‐evaluations in middle childhood |
title_sort | nature of the self: neural analyses and heritability estimates of self‐evaluations in middle childhood |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559501/ https://www.ncbi.nlm.nih.gov/pubmed/34477265 http://dx.doi.org/10.1002/hbm.25641 |
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