Kinetic sequencing (k-Seq) as a massively parallel assay for ribozyme kinetics: utility and critical parameters

Characterizing genotype-phenotype relationships of biomolecules (e.g. ribozymes) requires accurate ways to measure activity for a large set of molecules. Kinetic measurement using high-throughput sequencing (e.g. k-Seq) is an emerging assay applicable in various domains that potentially scales up me...

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Detalles Bibliográficos
Autores principales: Shen, Yuning, Pressman, Abe, Janzen, Evan, Chen, Irene A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559535/
https://www.ncbi.nlm.nih.gov/pubmed/33772580
http://dx.doi.org/10.1093/nar/gkab199

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