COVID-19 mRNA vaccine in pregnancy and newborn passive immunization: a case report

AIM: Evaluating the newborn passive immunization after maternal vaccination against SARS-COV-2. CASE PRESENTATION: We present the case of a pregnant woman, with no prior history of COVID-19 infection, who got her second dose of mRNA vaccine against SARS-COV-2, 3 days before the start of her spontane...

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Autores principales: Kassis, Nadine El, Abdallah, Wael, Chakra, Rim Abou, Arab, Wissam, Sassine, Serge, Atallah, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559592/
https://www.ncbi.nlm.nih.gov/pubmed/34900336
http://dx.doi.org/10.2144/fsoa-2021-0043
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author Kassis, Nadine El
Abdallah, Wael
Chakra, Rim Abou
Arab, Wissam
Sassine, Serge
Atallah, David
author_facet Kassis, Nadine El
Abdallah, Wael
Chakra, Rim Abou
Arab, Wissam
Sassine, Serge
Atallah, David
author_sort Kassis, Nadine El
collection PubMed
description AIM: Evaluating the newborn passive immunization after maternal vaccination against SARS-COV-2. CASE PRESENTATION: We present the case of a pregnant woman, with no prior history of COVID-19 infection, who got her second dose of mRNA vaccine against SARS-COV-2, 3 days before the start of her spontaneous labor. She was delivered by cesarean section after dynamical dystocia. Placental cord blood was retrieved immediately and sent to evaluate the titers of COVID-19 antibodies. Vaccine-generated antibodies were present in the umbilical cord with IgG spike >100 AU/ml. CONCLUSION: By reviewing the literature, vaccination seems to give hope about the potential protective effect of the maternal vaccination on her baby. Thus, pregnant women deserve a priority in the COVID-19 vaccination program.
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spelling pubmed-85595922021-11-03 COVID-19 mRNA vaccine in pregnancy and newborn passive immunization: a case report Kassis, Nadine El Abdallah, Wael Chakra, Rim Abou Arab, Wissam Sassine, Serge Atallah, David Future Sci OA Case Report AIM: Evaluating the newborn passive immunization after maternal vaccination against SARS-COV-2. CASE PRESENTATION: We present the case of a pregnant woman, with no prior history of COVID-19 infection, who got her second dose of mRNA vaccine against SARS-COV-2, 3 days before the start of her spontaneous labor. She was delivered by cesarean section after dynamical dystocia. Placental cord blood was retrieved immediately and sent to evaluate the titers of COVID-19 antibodies. Vaccine-generated antibodies were present in the umbilical cord with IgG spike >100 AU/ml. CONCLUSION: By reviewing the literature, vaccination seems to give hope about the potential protective effect of the maternal vaccination on her baby. Thus, pregnant women deserve a priority in the COVID-19 vaccination program. Future Science Ltd 2021-10-29 /pmc/articles/PMC8559592/ /pubmed/34900336 http://dx.doi.org/10.2144/fsoa-2021-0043 Text en © 2021 Nadine El Kassis https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Case Report
Kassis, Nadine El
Abdallah, Wael
Chakra, Rim Abou
Arab, Wissam
Sassine, Serge
Atallah, David
COVID-19 mRNA vaccine in pregnancy and newborn passive immunization: a case report
title COVID-19 mRNA vaccine in pregnancy and newborn passive immunization: a case report
title_full COVID-19 mRNA vaccine in pregnancy and newborn passive immunization: a case report
title_fullStr COVID-19 mRNA vaccine in pregnancy and newborn passive immunization: a case report
title_full_unstemmed COVID-19 mRNA vaccine in pregnancy and newborn passive immunization: a case report
title_short COVID-19 mRNA vaccine in pregnancy and newborn passive immunization: a case report
title_sort covid-19 mrna vaccine in pregnancy and newborn passive immunization: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559592/
https://www.ncbi.nlm.nih.gov/pubmed/34900336
http://dx.doi.org/10.2144/fsoa-2021-0043
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