CEP120-mediated KIAA0753 recruitment onto centrioles is required for timely neuronal differentiation and germinal zone exit in the developing cerebellum

Joubert syndrome (JS) is a recessive ciliopathy in which all affected individuals have congenital cerebellar vermis hypoplasia. Here, we report that CEP120, a JS-associated protein involved in centriole biogenesis and cilia assembly, regulates timely neuronal differentiation and the departure of gra...

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Detalles Bibliográficos
Autores principales: Chang, Chia-Hsiang, Chen, Ting-Yu, Lu, I-Ling, Li, Rong-Bin, Tsai, Jhih-Jie, Lin, Pin-Yeh, Tang, Tang K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559671/
https://www.ncbi.nlm.nih.gov/pubmed/34711653
http://dx.doi.org/10.1101/gad.348636.121

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