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Integrated loss- and gain-of-function screens define a core network governing human embryonic stem cell behavior

Understanding the genetic control of human embryonic stem cell function is foundational for developmental biology and regenerative medicine. Here we describe an integrated genome-scale loss- and gain-of-function screening approach to identify genetic networks governing embryonic stem cell proliferat...

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Detalles Bibliográficos
Autores principales:	Naxerova, Kamila, Di Stefano, Bruno, Makofske, Jessica L., Watson, Emma V., de Kort, Marit A., Martin, Timothy D., Dezfulian, Mohammed, Ricken, Dominik, Wooten, Eric C., Kuroda, Mitzi I., Hochedlinger, Konrad, Elledge, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2021
Materias:	Resource/Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559676/ https://www.ncbi.nlm.nih.gov/pubmed/34711655 http://dx.doi.org/10.1101/gad.349048.121

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