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Embryonic LTR retrotransposons supply promoter modules to somatic tissues

Long terminal repeat (LTR) retrotransposons are widely distributed across the human genome. They have accumulated through retroviral integration into germline DNA and are latent genetic modules. Active LTR promoters are observed in germline cells; however, little is known about the mechanisms underl...

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Detalles Bibliográficos
Autores principales: Hashimoto, Kosuke, Jouhilahti, Eeva-Mari, Töhönen, Virpi, Carninci, Piero, Kere, Juha, Katayama, Shintaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559712/
https://www.ncbi.nlm.nih.gov/pubmed/34675070
http://dx.doi.org/10.1101/gr.275354.121