Ultrasound-targeted simvastatin-loaded microbubble destruction promotes OA cartilage repair by modulating the cholesterol efflux pathway mediated by PPARγ in rabbits

AIMS: To evaluate the effect of ultrasound-targeted simvastatin-loaded microbubble destruction (UTMD (SV) ) for alleviation of the progression of osteoarthritis (OA) in rabbits through modulation of the peroxisome proliferator-activated receptor (PPARγ). METHODS: In vitro, OA chondrocytes were treat...

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Detalles Bibliográficos
Autores principales: Wang, Xinwei, Wang, Danbi, Xia, Peng, Cheng, Kai, Wang, Qi, Wang, Xiaoju, Lin, Qiang, Song, Jiulong, Chen, Anliang, Li, Xueping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2021
Materias:
Hip
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559971/
https://www.ncbi.nlm.nih.gov/pubmed/34666502
http://dx.doi.org/10.1302/2046-3758.1010.BJR-2021-0162.R3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559971/
https://www.ncbi.nlm.nih.gov/pubmed/34666502
http://dx.doi.org/10.1302/2046-3758.1010.BJR-2021-0162.R3

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