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Ultrasound-targeted simvastatin-loaded microbubble destruction promotes OA cartilage repair by modulating the cholesterol efflux pathway mediated by PPARγ in rabbits
AIMS: To evaluate the effect of ultrasound-targeted simvastatin-loaded microbubble destruction (UTMD (SV) ) for alleviation of the progression of osteoarthritis (OA) in rabbits through modulation of the peroxisome proliferator-activated receptor (PPARγ). METHODS: In vitro, OA chondrocytes were treat...
Autores principales: | Wang, Xinwei, Wang, Danbi, Xia, Peng, Cheng, Kai, Wang, Qi, Wang, Xiaoju, Lin, Qiang, Song, Jiulong, Chen, Anliang, Li, Xueping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The British Editorial Society of Bone & Joint Surgery
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559971/ https://www.ncbi.nlm.nih.gov/pubmed/34666502 http://dx.doi.org/10.1302/2046-3758.1010.BJR-2021-0162.R3 |
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