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AKAP79 enables calcineurin to directly suppress protein kinase A activity

Interplay between the second messengers cAMP and Ca(2+) is a hallmark of dynamic cellular processes. A common motif is the opposition of the Ca(2+)-sensitive phosphatase calcineurin and the major cAMP receptor, protein kinase A (PKA). Calcineurin dephosphorylates sites primed by PKA to bring about c...

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Detalles Bibliográficos
Autores principales:	Church, Timothy W, Tewatia, Parul, Hannan, Saad, Antunes, João, Eriksson, Olivia, Smart, Trevor G, Hellgren Kotaleski, Jeanette, Gold, Matthew G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560092/ https://www.ncbi.nlm.nih.gov/pubmed/34612814 http://dx.doi.org/10.7554/eLife.68164

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