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Rapid Improvement of Itch Associated With Atopic Dermatitis With Abrocitinib Is Partially Independent of Overall Disease Improvement: Results From Pooled Phase 2b and 3 Monotherapy Studies

BACKGROUND: Itch, the most bothersome symptom in atopic dermatitis, is largely mediated by pruritogenic cytokines via Janus kinase 1 signaling in cutaneous sensory neurons. OBJECTIVES: The aims of the study were to assess the magnitude and rapidity of itch relief with the Janus kinase 1 selective in...

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Detalles Bibliográficos
Autores principales:	Kim, Brian S., Silverberg, Jonathan I., Ständer, Sonja, Yosipovitch, Gil, Simpson, Eric L., DiBonaventura, Marco, Kerkmann, Urs, Farooqui, Saleem A., Biswas, Pinaki, Valdez, Hernan, Cameron, Michael C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560158/ https://www.ncbi.nlm.nih.gov/pubmed/34175862 http://dx.doi.org/10.1097/DER.0000000000000770

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