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From “East vs West” towards international multidisciplinary collaboration: An appraisal of lateral lymph nodes in rectal cancer

Western and Eastern practices have traditionally differed in their approach to treating lateral lymph nodes in rectal cancer. While Western clinicians have primarily favored neoadjuvant (chemo)radiotherapy to sterilize lateral compartments, Eastern physicians have often opted for the surgical remove...

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Detalles Bibliográficos
Autores principales: Sluckin, Tania C., Hazen, Sanne‐Marije J. A., Kusters, Miranda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560594/
https://www.ncbi.nlm.nih.gov/pubmed/34755004
http://dx.doi.org/10.1002/ags3.12490
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author Sluckin, Tania C.
Hazen, Sanne‐Marije J. A.
Kusters, Miranda
author_facet Sluckin, Tania C.
Hazen, Sanne‐Marije J. A.
Kusters, Miranda
author_sort Sluckin, Tania C.
collection PubMed
description Western and Eastern practices have traditionally differed in their approach to treating lateral lymph nodes in rectal cancer. While Western clinicians have primarily favored neoadjuvant (chemo)radiotherapy to sterilize lateral compartments, Eastern physicians have often opted for the surgical removed of lymphatic tissue with a lateral lymph node dissection without neoadjuvant treatment. The literature suggests similar oncological outcomes for these two separate techniques, while tangible differences exist. The combination of these paradigms may be beneficial in reducing overall morbidity while sustaining low recurrence rates. This article considers traditional Eastern and Western perspectives, discusses nodal features important for predicting malignancy and attempts to stimulate international, multidisciplinary consensus and collaboration.
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spelling pubmed-85605942021-11-08 From “East vs West” towards international multidisciplinary collaboration: An appraisal of lateral lymph nodes in rectal cancer Sluckin, Tania C. Hazen, Sanne‐Marije J. A. Kusters, Miranda Ann Gastroenterol Surg Review Articles Western and Eastern practices have traditionally differed in their approach to treating lateral lymph nodes in rectal cancer. While Western clinicians have primarily favored neoadjuvant (chemo)radiotherapy to sterilize lateral compartments, Eastern physicians have often opted for the surgical removed of lymphatic tissue with a lateral lymph node dissection without neoadjuvant treatment. The literature suggests similar oncological outcomes for these two separate techniques, while tangible differences exist. The combination of these paradigms may be beneficial in reducing overall morbidity while sustaining low recurrence rates. This article considers traditional Eastern and Western perspectives, discusses nodal features important for predicting malignancy and attempts to stimulate international, multidisciplinary consensus and collaboration. John Wiley and Sons Inc. 2021-08-09 /pmc/articles/PMC8560594/ /pubmed/34755004 http://dx.doi.org/10.1002/ags3.12490 Text en © 2021 The Authors. Annals of Gastroenterological Surgery published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Gastroenterology https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Review Articles
Sluckin, Tania C.
Hazen, Sanne‐Marije J. A.
Kusters, Miranda
From “East vs West” towards international multidisciplinary collaboration: An appraisal of lateral lymph nodes in rectal cancer
title From “East vs West” towards international multidisciplinary collaboration: An appraisal of lateral lymph nodes in rectal cancer
title_full From “East vs West” towards international multidisciplinary collaboration: An appraisal of lateral lymph nodes in rectal cancer
title_fullStr From “East vs West” towards international multidisciplinary collaboration: An appraisal of lateral lymph nodes in rectal cancer
title_full_unstemmed From “East vs West” towards international multidisciplinary collaboration: An appraisal of lateral lymph nodes in rectal cancer
title_short From “East vs West” towards international multidisciplinary collaboration: An appraisal of lateral lymph nodes in rectal cancer
title_sort from “east vs west” towards international multidisciplinary collaboration: an appraisal of lateral lymph nodes in rectal cancer
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560594/
https://www.ncbi.nlm.nih.gov/pubmed/34755004
http://dx.doi.org/10.1002/ags3.12490
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