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Shedding of Trypanosoma cruzi Surface Molecules That Regulate Host Cell Invasion Involves Phospholipase C and Increases Upon Sterol Depletion

Metacyclic trypomastigote (MT) forms of Trypanosoma cruzi have been shown to release into medium gp82 and gp90, the stage-specific surface molecules that regulate host cell invasion, either in vesicles or in soluble form. Here, we found that during interaction of poorly invasive G strain with the ho...

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Detalles Bibliográficos
Autores principales: Loch, Leonardo, Onofre, Thiago Souza, Rodrigues, João Paulo Ferreira, Yoshida, Nobuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560688/
https://www.ncbi.nlm.nih.gov/pubmed/34737979
http://dx.doi.org/10.3389/fcimb.2021.769722