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Novel Natural Inhibitors Targeting Enhancer of Zeste Homolog 2: A Comprehensive Structural Biology Research
The enhancer of zeste homolog 2 (EZH2) is a methylated modification enzyme of Histone H3-Lys 27. The high expression of EZH2 in cells is closely related to the progression, invasion, and metastasis of neoplasm. Therefore, this target is gradually becoming one of the research hot spots of tumor patho...
Autores principales: | Li, Weihang, Ding, Ziyi, Zhao, Yunlong, Jiang, Min, Zhang, Shilei, Zhao, Hongzhe, Lei, Ke, Xu, Rui, Zhao, Yingjing, Wang, Dong, Chao, Min, Yin, Yanjiang, Yang, Changbin, Wang, Liang, Yan, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560702/ https://www.ncbi.nlm.nih.gov/pubmed/34737956 http://dx.doi.org/10.3389/fonc.2021.741403 |
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