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PERK signaling through C/EBPδ contributes to ER stress-induced expression of immunomodulatory and tumor promoting chemokines by cancer cells

Cancer cells experience endoplasmic reticulum (ER) stress due to activated oncogenes and conditions of nutrient deprivation and hypoxia. The ensuing unfolded protein response (UPR) is executed by ATF6, IRE1 and PERK pathways. Adaptation to mild ER stress promotes tumor cell survival and aggressivene...

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Detalles Bibliográficos
Autores principales:	Sheshadri, Namratha, Poria, Dipak K., Sharan, Shikha, Hu, Ying, Yan, Chunhua, Koparde, Vishal N., Balamurugan, Kuppusamy, Sterneck, Esta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560861/ https://www.ncbi.nlm.nih.gov/pubmed/34725321 http://dx.doi.org/10.1038/s41419-021-04318-y

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