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Paradoxical implication of BAX/BAK in the persistence of tetraploid cells

Pro-apoptotic multi-domain proteins of the BCL2 family such as BAX and BAK are well known for their important role in the induction of mitochondrial outer membrane permeabilization (MOMP), which is the rate-limiting step of the intrinsic pathway of apoptosis. Human or mouse cells lacking both BAX an...

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Detalles Bibliográficos
Autores principales:	Deng, Jiayin, Gutiérrez, Lucía G., Stoll, Gautier, Motiño, Omar, Martins, Isabelle, Núñez, Lucía, Bravo-San Pedro, José Manuel, Humeau, Juliette, Bordenave, Chloé, Pan, Juncheng, Fohrer-Ting, Hélène, Souquere, Sylvie, Pierron, Gerard, Hetz, Claudio, Villalobos, Carlos, Kroemer, Guido, Senovilla, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560871/ https://www.ncbi.nlm.nih.gov/pubmed/34725331 http://dx.doi.org/10.1038/s41419-021-04321-3

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