EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1

The Hippo pathway is frequently dysregulated in cancer, leading to the unrestrained activity of its downstream targets, YAP/TAZ, and aberrant tumor growth. However, the precise mechanisms leading to YAP/TAZ activation in most cancers is still poorly understood. Analysis of large tissue collections r...

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Detalles Bibliográficos
Autores principales: Ando, Toshinori, Arang, Nadia, Wang, Zhiyong, Costea, Daniela Elena, Feng, Xiaodong, Goto, Yusuke, Izumi, Hiroki, Gilardi, Mara, Ando, Kazuyo, Gutkind, J. Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560880/
https://www.ncbi.nlm.nih.gov/pubmed/34725466
http://dx.doi.org/10.1038/s42003-021-02744-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560880/
https://www.ncbi.nlm.nih.gov/pubmed/34725466
http://dx.doi.org/10.1038/s42003-021-02744-4

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