Cargando…
EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1
The Hippo pathway is frequently dysregulated in cancer, leading to the unrestrained activity of its downstream targets, YAP/TAZ, and aberrant tumor growth. However, the precise mechanisms leading to YAP/TAZ activation in most cancers is still poorly understood. Analysis of large tissue collections r...
Autores principales: | Ando, Toshinori, Arang, Nadia, Wang, Zhiyong, Costea, Daniela Elena, Feng, Xiaodong, Goto, Yusuke, Izumi, Hiroki, Gilardi, Mara, Ando, Kazuyo, Gutkind, J. Silvio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560880/ https://www.ncbi.nlm.nih.gov/pubmed/34725466 http://dx.doi.org/10.1038/s42003-021-02744-4 |
Ejemplares similares
-
Muscarinic receptors promote castration resistant growth of prostate cancer through a FAK-YAP signaling axis
por: Goto, Yusuke, et al.
Publicado: (2020) -
Integrating Genetic Alterations and the Hippo Pathway in Head and Neck Squamous Cell Carcinoma for Future Precision Medicine
por: Ando, Toshinori, et al.
Publicado: (2022) -
Oncotargeting G proteins: The Hippo in the room
por: Feng, Xiaodong, et al.
Publicado: (2014) -
Mob Family Proteins: Regulatory Partners in Hippo and Hippo-Like Intracellular Signaling Pathways
por: Duhart, Juan Carlos, et al.
Publicado: (2020) -
MOB (Mps one Binder) Proteins in the Hippo Pathway and Cancer
por: Gundogdu, Ramazan, et al.
Publicado: (2019)