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Quality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer

This study aimed to assess the impact of the margin applied to the clinical target volume, to create the planning target volume, on plan quality of a novel dysphagia-optimised intensity modulated radiotherapy technique developed within a head and neck cancer multicentre randomised controlled trial....

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Detalles Bibliográficos
Autores principales: Tyler, Justine, Bernstein, David, Seithel, Matthew, Rooney, Keith, Petkar, Imran, Miles, Elizabeth, Clark, Catharine H, Hall, Emma, Nutting, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560997/
https://www.ncbi.nlm.nih.gov/pubmed/34754954
http://dx.doi.org/10.1016/j.phro.2021.10.003
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author Tyler, Justine
Bernstein, David
Seithel, Matthew
Rooney, Keith
Petkar, Imran
Miles, Elizabeth
Clark, Catharine H
Hall, Emma
Nutting, Chris
author_facet Tyler, Justine
Bernstein, David
Seithel, Matthew
Rooney, Keith
Petkar, Imran
Miles, Elizabeth
Clark, Catharine H
Hall, Emma
Nutting, Chris
author_sort Tyler, Justine
collection PubMed
description This study aimed to assess the impact of the margin applied to the clinical target volume, to create the planning target volume, on plan quality of a novel dysphagia-optimised intensity modulated radiotherapy technique developed within a head and neck cancer multicentre randomised controlled trial. Protocol compliant plans were used for a single benchmark planning case. Larger margins were associated with higher doses to adjacent organs at risk, particularly the inferior pharyngeal constrictor muscle, but coincided with some improved low dose target coverage. A 3 mm margin is recommended for this technique if local practices allow.
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spelling pubmed-85609972021-11-08 Quality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer Tyler, Justine Bernstein, David Seithel, Matthew Rooney, Keith Petkar, Imran Miles, Elizabeth Clark, Catharine H Hall, Emma Nutting, Chris Phys Imaging Radiat Oncol Short Communication This study aimed to assess the impact of the margin applied to the clinical target volume, to create the planning target volume, on plan quality of a novel dysphagia-optimised intensity modulated radiotherapy technique developed within a head and neck cancer multicentre randomised controlled trial. Protocol compliant plans were used for a single benchmark planning case. Larger margins were associated with higher doses to adjacent organs at risk, particularly the inferior pharyngeal constrictor muscle, but coincided with some improved low dose target coverage. A 3 mm margin is recommended for this technique if local practices allow. Elsevier 2021-10-26 /pmc/articles/PMC8560997/ /pubmed/34754954 http://dx.doi.org/10.1016/j.phro.2021.10.003 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Short Communication
Tyler, Justine
Bernstein, David
Seithel, Matthew
Rooney, Keith
Petkar, Imran
Miles, Elizabeth
Clark, Catharine H
Hall, Emma
Nutting, Chris
Quality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer
title Quality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer
title_full Quality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer
title_fullStr Quality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer
title_full_unstemmed Quality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer
title_short Quality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer
title_sort quality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560997/
https://www.ncbi.nlm.nih.gov/pubmed/34754954
http://dx.doi.org/10.1016/j.phro.2021.10.003
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