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Catalytic and structural insights into a stereospecific and thermostable Class II aldolase HpaI from Acinetobacter baumannii

Aldolases catalyze the reversible reactions of aldol condensation and cleavage and have strong potential for the synthesis of chiral compounds, widely used in pharmaceuticals. Here, we investigated a new Class II metal aldolase from the p-hydroxyphenylacetate degradation pathway in Acinetobacter bau...

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Detalles Bibliográficos
Autores principales: Watthaisong, Pratchaya, Binlaeh, Asweena, Jaruwat, Aritsara, Lawan, Narin, Tantipisit, Jirawat, Jaroensuk, Juthamas, Chuaboon, Litavadee, Phonbuppha, Jittima, Tinikul, Ruchanok, Chaiyen, Pimchai, Chitnumsub, Penchit, Maenpuen, Somchart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560999/
https://www.ncbi.nlm.nih.gov/pubmed/34624314
http://dx.doi.org/10.1016/j.jbc.2021.101280

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