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The Sigma-1 receptor is an ER-localized type II membrane protein

The Sigma-1 receptor (S1R) is a transmembrane protein with important roles in cellular homeostasis in normal physiology and in disease. Especially in neurodegenerative diseases, S1R activation has been shown to provide neuroprotection by modulating calcium signaling, mitochondrial function and reduc...

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Detalles Bibliográficos
Autores principales:	Sharma, Neeraj, Patel, Chaitanya, Shenkman, Marina, Kessel, Amit, Ben-Tal, Nir, Lederkremer, Gerardo Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561001/ https://www.ncbi.nlm.nih.gov/pubmed/34648767 http://dx.doi.org/10.1016/j.jbc.2021.101299

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