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The cell surface hyaluronidase TMEM2 is essential for systemic hyaluronan catabolism and turnover

As a major component of the extracellular matrix, hyaluronan (HA) plays an important role in defining the biochemical and biophysical properties of tissues. In light of the extremely rapid turnover of HA and the impact of this turnover on HA biology, elucidating the molecular mechanisms underlying H...

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Detalles Bibliográficos
Autores principales: Tobisawa, Yuki, Fujita, Naoki, Yamamoto, Hayato, Ohyama, Chikara, Irie, Fumitoshi, Yamaguchi, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561002/
https://www.ncbi.nlm.nih.gov/pubmed/34624311
http://dx.doi.org/10.1016/j.jbc.2021.101281