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Kynurenine pathway activation and deviation to anthranilic and kynurenic acid in fibrosing chronic graft-versus-host disease

Fibrosing chronic graft-versus-host disease (cGVHD) is a debilitating complication of allogeneic stem cell transplantation (alloSCT). A driver of fibrosis is the kynurenine (Kyn) pathway, and Kyn metabolism patterns and cytokines may influence cGVHD severity and manifestation (fibrosing versus gastr...

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Detalles Bibliográficos
Autores principales:	Orsatti, Laura, Stiehl, Thomas, Dischinger, Katharina, Speziale, Roberto, Di Pasquale, Pamela, Monteagudo, Edith, Müller-Tidow, Carsten, Radujkovic, Aleksandar, Dreger, Peter, Luft, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561165/ https://www.ncbi.nlm.nih.gov/pubmed/34755129 http://dx.doi.org/10.1016/j.xcrm.2021.100409

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