Targeting folate receptor beta on monocytes/macrophages renders rapid inflammation resolution independent of root causes

Provoked by sterile/nonsterile insults, prolonged monocyte mobilization and uncontrolled monocyte/macrophage activation can pose imminent or impending harm to the affected organs. Curiously, folate receptor beta (FRβ), with subnanomolar affinity for the vitamin folic acid (FA), is upregulated during...

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Detalles Bibliográficos
Autores principales: Lu, Yingjuan J., Wheeler, Leroy W., Chu, Haiyan, Kleindl, Paul J., Pugh, Michael, You, Fei, Rao, Satish, Garcia, Gabriela, Wu, Henry Y., da Cunha, Andre P., Johnson, Richard, Westrick, Elaine, Cross, Vicky, Lloyd, Alex, Dircksen, Christina, Klein, Patrick J., Vlahov, Iontcho R., Low, Philip S., Leamon, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561236/
https://www.ncbi.nlm.nih.gov/pubmed/34755134
http://dx.doi.org/10.1016/j.xcrm.2021.100422

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