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The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality

Band 3 (anion exchanger 1; AE1) is the most abundant membrane protein in red blood cells, which in turn are the most abundant cells in the human body. A compelling model posits that, at high oxygen saturation, the N-terminal cytosolic domain of AE1 binds to and inhibits glycolytic enzymes, thus dive...

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Detalles Bibliográficos
Autores principales: Issaian, Aaron, Hay, Ariel, Dzieciatkowska, Monika, Roberti, Domenico, Perrotta, Silverio, Darula, Zsuzsanna, Redzic, Jasmina, Busch, Micheal P., Page, Grier P., Rogers, Stephen C., Doctor, Allan, Hansen, Kirk C., Eisenmesser, Elan Z., Zimring, James C., D’Alessandro, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561282/
https://www.ncbi.nlm.nih.gov/pubmed/33979990
http://dx.doi.org/10.3324/haematol.2020.278252