Characterization and evolutionary origin of novel C2H2 zinc finger protein (ZNF648) required for both erythroid and megakaryocyte differentiation in humans

Human ZNF648 is a novel poly C-terminal C2H2 zinc finger (ZnF) protein identified amongst the most dysregulated proteins in erythroid cells differentiated from induced pluripotent stem cells. Its nuclear localization and structure indicate it is likely a DNA-binding protein. Using a combination of Z...

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Detalles Bibliográficos
Autores principales: Ferguson, Daniel C. J., Mokim, Juraidah Haji, Meinders, Marjolein, Moody, Edmund R. R., Williams, Tom A., Cooke, Sarah, Trakarnsanga, Kongtana, Daniels, Deborah E., Ferrer-Vicens, Ivan, Shoemark, Deborah, Tipgomut, Chartsiam, Macinnes, Katherine A., Wilson, Marieangela C., Singleton, Belinda K., Frayne, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561289/
https://www.ncbi.nlm.nih.gov/pubmed/33054117
http://dx.doi.org/10.3324/haematol.2020.256347

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