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Multi-omic evaluation of metabolic alterations in multiple sclerosis identifies shifts in aromatic amino acid metabolism

The circulating metabolome provides unique insights into multiple sclerosis (MS) pathophysiology, but existing studies are relatively small or characterized limited metabolites. We test for differences in the metabolome between people with MS (PwMS; n = 637 samples) and healthy controls (HC; n = 317...

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Detalles Bibliográficos
Autores principales:	Fitzgerald, Kathryn C., Smith, Matthew D., Kim, Sol, Sotirchos, Elias S., Kornberg, Michael D., Douglas, Morgan, Nourbakhsh, Bardia, Graves, Jennifer, Rattan, Ramandeep, Poisson, Laila, Cerghet, Mirela, Mowry, Ellen M., Waubant, Emmanuelle, Giri, Shailendra, Calabresi, Peter A., Bhargava, Pavan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561319/ https://www.ncbi.nlm.nih.gov/pubmed/34755135 http://dx.doi.org/10.1016/j.xcrm.2021.100424

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