Aberrant lung lipids cause respiratory impairment in a Mecp2-deficient mouse model of Rett syndrome

Severe respiratory impairment is a prominent feature of Rett syndrome, an X-linked disorder caused by mutations in methyl CpG-binding protein 2 (MECP2). Despite MECP2’s ubiquitous expression, respiratory anomalies are attributed to neuronal dysfunction. Here, we show that neutral lipids accumulate i...

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Detalles Bibliográficos
Autores principales: Vashi, Neeti, Ackerley, Cameron, Post, Martin, Justice, Monica J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561422/
https://www.ncbi.nlm.nih.gov/pubmed/34230964
http://dx.doi.org/10.1093/hmg/ddab182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561422/
https://www.ncbi.nlm.nih.gov/pubmed/34230964
http://dx.doi.org/10.1093/hmg/ddab182

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