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Non‐genetic and genetic rewiring underlie adaptation to hypomorphic alleles of an essential gene

Adaptive evolution to cellular stress is a process implicated in a wide range of biological and clinical phenomena. Two major routes of adaptation have been identified: non‐genetic changes, which allow expression of different phenotypes in novel environments, and genetic variation achieved by select...

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Detalles Bibliográficos
Autores principales: Targa, Altea, Larrimore, Katherine E, Wong, Cheng Kit, Chong, Yu Lin, Fung, Ronald, Lee, Joseph, Choi, Hyungwon, Rancati, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561638/
https://www.ncbi.nlm.nih.gov/pubmed/34528284
http://dx.doi.org/10.15252/embj.2021107839

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