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Non‐genetic and genetic rewiring underlie adaptation to hypomorphic alleles of an essential gene
Adaptive evolution to cellular stress is a process implicated in a wide range of biological and clinical phenomena. Two major routes of adaptation have been identified: non‐genetic changes, which allow expression of different phenotypes in novel environments, and genetic variation achieved by select...
Autores principales: | Targa, Altea, Larrimore, Katherine E, Wong, Cheng Kit, Chong, Yu Lin, Fung, Ronald, Lee, Joseph, Choi, Hyungwon, Rancati, Giulia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561638/ https://www.ncbi.nlm.nih.gov/pubmed/34528284 http://dx.doi.org/10.15252/embj.2021107839 |
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