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Chaperone-Mediated Stress Sensing in Mycobacterium tuberculosis Enables Fast Activation and Sustained Response
Dynamical properties of gene regulatory networks are tuned to ensure bacterial survival. In mycobacteria, the MprAB-σ(E) network responds to the presence of stressors, such as surfactants that cause surface stress. Positive feedback loops in this network were previously predicted to cause hysteresis...
Autores principales: | Rao, Satyajit D., Datta, Pratik, Gennaro, Maria Laura, Igoshin, Oleg A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561658/ https://www.ncbi.nlm.nih.gov/pubmed/33594002 http://dx.doi.org/10.1128/mSystems.00979-20 |
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