P62 accumulates through neuroanatomical circuits in response to tauopathy propagation

In Alzheimer’s disease and related tauopathies, trans-synaptic transfer and accumulation of pathological tau from donor to recipient neurons is thought to contribute to disease progression, but the underlying mechanisms are poorly understood. Using complementary in vivo and in vitro models, we exami...

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Detalles Bibliográficos
Autores principales: Blaudin de Thé, François-Xavier, Lassus, Benjamin, Schaler, Ari W., Fowler, Stephanie L., Goulbourne, Chris N., Jeggo, Ross, Mannoury la Cour, Clotilde, Millan, Mark J., Duff, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561893/
https://www.ncbi.nlm.nih.gov/pubmed/34727983
http://dx.doi.org/10.1186/s40478-021-01280-w

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