A non-internalised CD38-binding radiolabelled single-domain antibody fragment to monitor and treat multiple myeloma

BACKGROUND: Antibody-based therapies targeting CD38 are currently used as single agents as well as in combination regimens for multiple myeloma, a malignant plasma cell disorder. In this study, we aimed to develop anti-CD38 single-domain antibodies (sdAbs) that can be used to trace CD38(+) tumour ce...

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Detalles Bibliográficos
Autores principales: Duray, Elodie, Lejeune, Margaux, Baron, Frederic, Beguin, Yves, Devoogdt, Nick, Krasniqi, Ahmet, Lauwers, Yoline, Zhao, Yong Juan, D’Huyvetter, Matthias, Dumoulin, Mireille, Caers, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8561907/
https://www.ncbi.nlm.nih.gov/pubmed/34727950
http://dx.doi.org/10.1186/s13045-021-01171-6

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