Astrocytes and retrograde degeneration of nigrostriatal dopaminergic neurons in Parkinson’s disease: removing axonal debris

OBJECTIVE: The dopaminergic nigrostriatal neurons (DA cells) in healthy people present a slow degeneration with aging, which produces cellular debris throughout life. About 2%–5% of people present rapid cell degeneration of more than 50% of DA cells, which produces Parkinson’s disease (PD). Neuroinf...

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Detalles Bibliográficos
Autores principales: Morales, Ingrid, Puertas-Avendaño, Ricardo, Sanchez, Alberto, Perez-Barreto, Adrian, Rodriguez-Sabate, Clara, Rodriguez, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562009/
https://www.ncbi.nlm.nih.gov/pubmed/34727977
http://dx.doi.org/10.1186/s40035-021-00262-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562009/
https://www.ncbi.nlm.nih.gov/pubmed/34727977
http://dx.doi.org/10.1186/s40035-021-00262-1

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