Cargando…
Astrocytes and retrograde degeneration of nigrostriatal dopaminergic neurons in Parkinson’s disease: removing axonal debris
OBJECTIVE: The dopaminergic nigrostriatal neurons (DA cells) in healthy people present a slow degeneration with aging, which produces cellular debris throughout life. About 2%–5% of people present rapid cell degeneration of more than 50% of DA cells, which produces Parkinson’s disease (PD). Neuroinf...
Autores principales: | Morales, Ingrid, Puertas-Avendaño, Ricardo, Sanchez, Alberto, Perez-Barreto, Adrian, Rodriguez-Sabate, Clara, Rodriguez, Manuel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562009/ https://www.ncbi.nlm.nih.gov/pubmed/34727977 http://dx.doi.org/10.1186/s40035-021-00262-1 |
Ejemplares similares
-
Striatal astrocytes engulf dopaminergic debris in Parkinson's disease: A study in an animal model
por: Morales, Ingrid, et al.
Publicado: (2017) -
Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit
por: Pham, Anh H., et al.
Publicado: (2012) -
A Mouse Model of Nigrostriatal Dopaminergic Axonal Degeneration As a Tool for Testing Neuroprotectors
por: Kolacheva, A. A., et al.
Publicado: (2021) -
Clinical Features Indicating Nigrostriatal Dopaminergic Degeneration in Drug-Induced Parkinsonism
por: Lee, Seung Ha, et al.
Publicado: (2017) -
The dynamic of basal ganglia activity with a multiple covariance method: influences of Parkinson’s disease
por: Rodriguez-Sabate, Clara, et al.
Publicado: (2019)