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On the effect of the number of tests and their time of application in tracing policies against COVID-19.

In this paper we explore the effect of the number of daily tests on an epidemics control policy purely based on testing and selective quarantine, and the impact of these actions depending on the time their application starts. We introduce a general model incorporating a stochastic disease evolution,...

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Detalles Bibliográficos
Autores principales: Rossello, Nicolas Bono, Pezzutto, Matthias, Schenato, Luca, Castagliuolo, Ignazio, Garone, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: , IFAC (International Federation of Automatic Control) Hosting by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562127/
http://dx.doi.org/10.1016/j.ifacol.2021.10.248
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author Rossello, Nicolas Bono
Pezzutto, Matthias
Schenato, Luca
Castagliuolo, Ignazio
Garone, Emanuele
author_facet Rossello, Nicolas Bono
Pezzutto, Matthias
Schenato, Luca
Castagliuolo, Ignazio
Garone, Emanuele
author_sort Rossello, Nicolas Bono
collection PubMed
description In this paper we explore the effect of the number of daily tests on an epidemics control policy purely based on testing and selective quarantine, and the impact of these actions depending on the time their application starts. We introduce a general model incorporating a stochastic disease evolution, a particular weighted graph representing the population, and an optimal contact tracing strategy to allocate available tests. Simulations on a community of 50’000 individuals show that the evolution of the epidemic produces a clear non-linear response to the variation of the number of tests used and to the starting time of their application. These results suggest that not only a minimum number of tests is necessary to obtain a positive outcome from the tracing strategy but also that there exists a saturation on the contribution of additional tests. The results also show that the timing in the application of the measures is as important as the measures themselves and that an excessive delay can be hardly overcome.
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spelling pubmed-85621272021-11-02 On the effect of the number of tests and their time of application in tracing policies against COVID-19. Rossello, Nicolas Bono Pezzutto, Matthias Schenato, Luca Castagliuolo, Ignazio Garone, Emanuele IFAC-PapersOnLine Article In this paper we explore the effect of the number of daily tests on an epidemics control policy purely based on testing and selective quarantine, and the impact of these actions depending on the time their application starts. We introduce a general model incorporating a stochastic disease evolution, a particular weighted graph representing the population, and an optimal contact tracing strategy to allocate available tests. Simulations on a community of 50’000 individuals show that the evolution of the epidemic produces a clear non-linear response to the variation of the number of tests used and to the starting time of their application. These results suggest that not only a minimum number of tests is necessary to obtain a positive outcome from the tracing strategy but also that there exists a saturation on the contribution of additional tests. The results also show that the timing in the application of the measures is as important as the measures themselves and that an excessive delay can be hardly overcome. , IFAC (International Federation of Automatic Control) Hosting by Elsevier Ltd. 2021 2021-11-02 /pmc/articles/PMC8562127/ http://dx.doi.org/10.1016/j.ifacol.2021.10.248 Text en © 2019, IFAC (International Federation of Automatic Control) Hosting by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Rossello, Nicolas Bono
Pezzutto, Matthias
Schenato, Luca
Castagliuolo, Ignazio
Garone, Emanuele
On the effect of the number of tests and their time of application in tracing policies against COVID-19.
title On the effect of the number of tests and their time of application in tracing policies against COVID-19.
title_full On the effect of the number of tests and their time of application in tracing policies against COVID-19.
title_fullStr On the effect of the number of tests and their time of application in tracing policies against COVID-19.
title_full_unstemmed On the effect of the number of tests and their time of application in tracing policies against COVID-19.
title_short On the effect of the number of tests and their time of application in tracing policies against COVID-19.
title_sort on the effect of the number of tests and their time of application in tracing policies against covid-19.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562127/
http://dx.doi.org/10.1016/j.ifacol.2021.10.248
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