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In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system
PURPOSE: The aim of the study was to evaluate the feasibility of a new venous-thrombus aspiration and autologous blood (auto-blood) reinfusion system. MATERIALS AND METHODS: We constructed the venous model from polyvinyl chloride (PVC) tubes and three-way unions using a fresh clot of chicken blood a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562152/ https://www.ncbi.nlm.nih.gov/pubmed/34805863 http://dx.doi.org/10.1016/j.jimed.2019.05.004 |
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author | Li, Weixiao Li, Qiang Zhai, Shuiting Li, Tianxiao Cheshire, Nick Zhang, Zhidong Liang, Kai |
author_facet | Li, Weixiao Li, Qiang Zhai, Shuiting Li, Tianxiao Cheshire, Nick Zhang, Zhidong Liang, Kai |
author_sort | Li, Weixiao |
collection | PubMed |
description | PURPOSE: The aim of the study was to evaluate the feasibility of a new venous-thrombus aspiration and autologous blood (auto-blood) reinfusion system. MATERIALS AND METHODS: We constructed the venous model from polyvinyl chloride (PVC) tubes and three-way unions using a fresh clot of chicken blood as the venous thrombus. Eight French and 12F aspiration catheters were used to aspirate the thrombus in the right–pulmonary-artery model, 8 French and 14F aspiration catheters were used in the inferior–vena cava model, and 8 French and 10F aspiration catheters were used in the left–iliofemoral-vein model. A thrombus filtration and auto-blood reinfusion bottle was used to filter the thrombus and re-infuse auto-blood. We evaluated the thrombus aspiration capability of each catheter by comparing pre-aspirated with the post-aspirated thrombus volume, and we evaluated the difference in aspiration capability between the two catheters in each model by comparing their thrombus aspiration rates. We used Student's t-test for statistical analysis. RESULTS: Differences between pre-aspirated and post-aspirated thrombus volumes for each catheter were insignificant, as were those between the thrombus aspiration rates of the two catheters in each venous model. Using the thrombus aspiration and auto-blood reinfusion system, each aspiration catheter could fluently aspirate the thrombus out of the venous model. CONCLUSION: In this study, we designed a new venous-thrombus aspiration system. This system could be used to aspirate acute venous thrombi and re-infuse autologous blood. |
format | Online Article Text |
id | pubmed-8562152 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-85621522021-11-19 In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system Li, Weixiao Li, Qiang Zhai, Shuiting Li, Tianxiao Cheshire, Nick Zhang, Zhidong Liang, Kai J Interv Med Article PURPOSE: The aim of the study was to evaluate the feasibility of a new venous-thrombus aspiration and autologous blood (auto-blood) reinfusion system. MATERIALS AND METHODS: We constructed the venous model from polyvinyl chloride (PVC) tubes and three-way unions using a fresh clot of chicken blood as the venous thrombus. Eight French and 12F aspiration catheters were used to aspirate the thrombus in the right–pulmonary-artery model, 8 French and 14F aspiration catheters were used in the inferior–vena cava model, and 8 French and 10F aspiration catheters were used in the left–iliofemoral-vein model. A thrombus filtration and auto-blood reinfusion bottle was used to filter the thrombus and re-infuse auto-blood. We evaluated the thrombus aspiration capability of each catheter by comparing pre-aspirated with the post-aspirated thrombus volume, and we evaluated the difference in aspiration capability between the two catheters in each model by comparing their thrombus aspiration rates. We used Student's t-test for statistical analysis. RESULTS: Differences between pre-aspirated and post-aspirated thrombus volumes for each catheter were insignificant, as were those between the thrombus aspiration rates of the two catheters in each venous model. Using the thrombus aspiration and auto-blood reinfusion system, each aspiration catheter could fluently aspirate the thrombus out of the venous model. CONCLUSION: In this study, we designed a new venous-thrombus aspiration system. This system could be used to aspirate acute venous thrombi and re-infuse autologous blood. KeAi Publishing 2019-06-27 /pmc/articles/PMC8562152/ /pubmed/34805863 http://dx.doi.org/10.1016/j.jimed.2019.05.004 Text en © 2019 Shanghai Journal of Interventional Medicine Press. Production and hosting by Elsevier B.V. on behalf of KeAi. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Li, Weixiao Li, Qiang Zhai, Shuiting Li, Tianxiao Cheshire, Nick Zhang, Zhidong Liang, Kai In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system |
title | In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system |
title_full | In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system |
title_fullStr | In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system |
title_full_unstemmed | In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system |
title_short | In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system |
title_sort | in vitro investigation of a new thrombus aspiration and autologous blood reinfusion system |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562152/ https://www.ncbi.nlm.nih.gov/pubmed/34805863 http://dx.doi.org/10.1016/j.jimed.2019.05.004 |
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