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In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system

PURPOSE: The aim of the study was to evaluate the feasibility of a new venous-thrombus aspiration and autologous blood (auto-blood) reinfusion system. MATERIALS AND METHODS: We constructed the venous model from polyvinyl chloride (PVC) tubes and three-way unions using a fresh clot of chicken blood a...

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Autores principales: Li, Weixiao, Li, Qiang, Zhai, Shuiting, Li, Tianxiao, Cheshire, Nick, Zhang, Zhidong, Liang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562152/
https://www.ncbi.nlm.nih.gov/pubmed/34805863
http://dx.doi.org/10.1016/j.jimed.2019.05.004
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author Li, Weixiao
Li, Qiang
Zhai, Shuiting
Li, Tianxiao
Cheshire, Nick
Zhang, Zhidong
Liang, Kai
author_facet Li, Weixiao
Li, Qiang
Zhai, Shuiting
Li, Tianxiao
Cheshire, Nick
Zhang, Zhidong
Liang, Kai
author_sort Li, Weixiao
collection PubMed
description PURPOSE: The aim of the study was to evaluate the feasibility of a new venous-thrombus aspiration and autologous blood (auto-blood) reinfusion system. MATERIALS AND METHODS: We constructed the venous model from polyvinyl chloride (PVC) tubes and three-way unions using a fresh clot of chicken blood as the venous thrombus. Eight French and 12F aspiration catheters were used to aspirate the thrombus in the right–pulmonary-artery model, 8 French and 14F aspiration catheters were used in the inferior–vena cava model, and 8 French and 10F aspiration catheters were used in the left–iliofemoral-vein model. A thrombus filtration and auto-blood reinfusion bottle was used to filter the thrombus and re-infuse auto-blood. We evaluated the thrombus aspiration capability of each catheter by comparing pre-aspirated with the post-aspirated thrombus volume, and we evaluated the difference in aspiration capability between the two catheters in each model by comparing their thrombus aspiration rates. We used Student's t-test for statistical analysis. RESULTS: Differences between pre-aspirated and post-aspirated thrombus volumes for each catheter were insignificant, as were those between the thrombus aspiration rates of the two catheters in each venous model. Using the thrombus aspiration and auto-blood reinfusion system, each aspiration catheter could fluently aspirate the thrombus out of the venous model. CONCLUSION: In this study, we designed a new venous-thrombus aspiration system. This system could be used to aspirate acute venous thrombi and re-infuse autologous blood.
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spelling pubmed-85621522021-11-19 In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system Li, Weixiao Li, Qiang Zhai, Shuiting Li, Tianxiao Cheshire, Nick Zhang, Zhidong Liang, Kai J Interv Med Article PURPOSE: The aim of the study was to evaluate the feasibility of a new venous-thrombus aspiration and autologous blood (auto-blood) reinfusion system. MATERIALS AND METHODS: We constructed the venous model from polyvinyl chloride (PVC) tubes and three-way unions using a fresh clot of chicken blood as the venous thrombus. Eight French and 12F aspiration catheters were used to aspirate the thrombus in the right–pulmonary-artery model, 8 French and 14F aspiration catheters were used in the inferior–vena cava model, and 8 French and 10F aspiration catheters were used in the left–iliofemoral-vein model. A thrombus filtration and auto-blood reinfusion bottle was used to filter the thrombus and re-infuse auto-blood. We evaluated the thrombus aspiration capability of each catheter by comparing pre-aspirated with the post-aspirated thrombus volume, and we evaluated the difference in aspiration capability between the two catheters in each model by comparing their thrombus aspiration rates. We used Student's t-test for statistical analysis. RESULTS: Differences between pre-aspirated and post-aspirated thrombus volumes for each catheter were insignificant, as were those between the thrombus aspiration rates of the two catheters in each venous model. Using the thrombus aspiration and auto-blood reinfusion system, each aspiration catheter could fluently aspirate the thrombus out of the venous model. CONCLUSION: In this study, we designed a new venous-thrombus aspiration system. This system could be used to aspirate acute venous thrombi and re-infuse autologous blood. KeAi Publishing 2019-06-27 /pmc/articles/PMC8562152/ /pubmed/34805863 http://dx.doi.org/10.1016/j.jimed.2019.05.004 Text en © 2019 Shanghai Journal of Interventional Medicine Press. Production and hosting by Elsevier B.V. on behalf of KeAi. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Li, Weixiao
Li, Qiang
Zhai, Shuiting
Li, Tianxiao
Cheshire, Nick
Zhang, Zhidong
Liang, Kai
In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system
title In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system
title_full In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system
title_fullStr In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system
title_full_unstemmed In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system
title_short In vitro investigation of a new thrombus aspiration and autologous blood reinfusion system
title_sort in vitro investigation of a new thrombus aspiration and autologous blood reinfusion system
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562152/
https://www.ncbi.nlm.nih.gov/pubmed/34805863
http://dx.doi.org/10.1016/j.jimed.2019.05.004
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