Radiation segmentectomy for hepatic malignancies: Indications, devices, dosimetry, procedure, clinical outcomes, and toxicity of yttrium-90 microspheres

Radiation segmentectomy (RS) is a new approach to (90)Y radioembolization that has been designed to increase the safety and efficacy of radioembolization in patients with unresectable hepatic malignancies. With this technique, high doses (>190 Gy) of radiation are delivered to the tumor through r...

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Autores principales: Jia, Zhongzhi, Wang, Caoye, Paz-Fumagalli, Ricardo, Wang, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562265/
https://www.ncbi.nlm.nih.gov/pubmed/34805860
http://dx.doi.org/10.1016/j.jimed.2019.05.001
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author Jia, Zhongzhi
Wang, Caoye
Paz-Fumagalli, Ricardo
Wang, Weiping
author_facet Jia, Zhongzhi
Wang, Caoye
Paz-Fumagalli, Ricardo
Wang, Weiping
author_sort Jia, Zhongzhi
collection PubMed
description Radiation segmentectomy (RS) is a new approach to (90)Y radioembolization that has been designed to increase the safety and efficacy of radioembolization in patients with unresectable hepatic malignancies. With this technique, high doses (>190 Gy) of radiation are delivered to the tumor through radioembolization performed in a segmental fashion, potentially increasing the radiation dose to the tumor while minimizing injury to the liver parenchyma. The aim of this review is to provide a summary of the indications, device choice, dosimetry, procedure, clinical outcomes, and toxicity of RS based on the clinical series currently available.
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spelling pubmed-85622652021-11-19 Radiation segmentectomy for hepatic malignancies: Indications, devices, dosimetry, procedure, clinical outcomes, and toxicity of yttrium-90 microspheres Jia, Zhongzhi Wang, Caoye Paz-Fumagalli, Ricardo Wang, Weiping J Interv Med Article Radiation segmentectomy (RS) is a new approach to (90)Y radioembolization that has been designed to increase the safety and efficacy of radioembolization in patients with unresectable hepatic malignancies. With this technique, high doses (>190 Gy) of radiation are delivered to the tumor through radioembolization performed in a segmental fashion, potentially increasing the radiation dose to the tumor while minimizing injury to the liver parenchyma. The aim of this review is to provide a summary of the indications, device choice, dosimetry, procedure, clinical outcomes, and toxicity of RS based on the clinical series currently available. KeAi Publishing 2019-06-27 /pmc/articles/PMC8562265/ /pubmed/34805860 http://dx.doi.org/10.1016/j.jimed.2019.05.001 Text en © 2019 Shanghai Journal of Interventional Medicine Press. Production and hosting by Elsevier B.V. on behalf of KeAi. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Jia, Zhongzhi
Wang, Caoye
Paz-Fumagalli, Ricardo
Wang, Weiping
Radiation segmentectomy for hepatic malignancies: Indications, devices, dosimetry, procedure, clinical outcomes, and toxicity of yttrium-90 microspheres
title Radiation segmentectomy for hepatic malignancies: Indications, devices, dosimetry, procedure, clinical outcomes, and toxicity of yttrium-90 microspheres
title_full Radiation segmentectomy for hepatic malignancies: Indications, devices, dosimetry, procedure, clinical outcomes, and toxicity of yttrium-90 microspheres
title_fullStr Radiation segmentectomy for hepatic malignancies: Indications, devices, dosimetry, procedure, clinical outcomes, and toxicity of yttrium-90 microspheres
title_full_unstemmed Radiation segmentectomy for hepatic malignancies: Indications, devices, dosimetry, procedure, clinical outcomes, and toxicity of yttrium-90 microspheres
title_short Radiation segmentectomy for hepatic malignancies: Indications, devices, dosimetry, procedure, clinical outcomes, and toxicity of yttrium-90 microspheres
title_sort radiation segmentectomy for hepatic malignancies: indications, devices, dosimetry, procedure, clinical outcomes, and toxicity of yttrium-90 microspheres
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562265/
https://www.ncbi.nlm.nih.gov/pubmed/34805860
http://dx.doi.org/10.1016/j.jimed.2019.05.001
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AT pazfumagalliricardo radiationsegmentectomyforhepaticmalignanciesindicationsdevicesdosimetryprocedureclinicaloutcomesandtoxicityofyttrium90microspheres
AT wangweiping radiationsegmentectomyforhepaticmalignanciesindicationsdevicesdosimetryprocedureclinicaloutcomesandtoxicityofyttrium90microspheres

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