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Clinical presentation, complications, and outcomes of hospitalized COVID‐19 patients in an academic center with a centralized palliative care consult service

BACKGROUND AND AIMS: Palliative care is a critical component of the response of a healthcare system to a pandemic. We present risk factors associated with mortality and highlight an operational palliative care consult service in facilitating early identification of risk factors to guide goal‐concord...

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Autores principales: Baker, Sarah M., Leedy, Doug J., Klafter, Jesse Abbott, Zhang, Yilin, Secrest, Kayla M., Osborn, Tristan R., Cheng, Richard K., Judson, Seth D., Merel, Susan E., Mikacenic, Carmen, Bhatraju, Pavan K., Liles, W. Conrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562312/
https://www.ncbi.nlm.nih.gov/pubmed/34754946
http://dx.doi.org/10.1002/hsr2.423
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author Baker, Sarah M.
Leedy, Doug J.
Klafter, Jesse Abbott
Zhang, Yilin
Secrest, Kayla M.
Osborn, Tristan R.
Cheng, Richard K.
Judson, Seth D.
Merel, Susan E.
Mikacenic, Carmen
Bhatraju, Pavan K.
Liles, W. Conrad
author_facet Baker, Sarah M.
Leedy, Doug J.
Klafter, Jesse Abbott
Zhang, Yilin
Secrest, Kayla M.
Osborn, Tristan R.
Cheng, Richard K.
Judson, Seth D.
Merel, Susan E.
Mikacenic, Carmen
Bhatraju, Pavan K.
Liles, W. Conrad
author_sort Baker, Sarah M.
collection PubMed
description BACKGROUND AND AIMS: Palliative care is a critical component of the response of a healthcare system to a pandemic. We present risk factors associated with mortality and highlight an operational palliative care consult service in facilitating early identification of risk factors to guide goal‐concordant care and rational utilization of finite healthcare resources during a pandemic. METHODS: In this case series of 100 consecutive patients hospitalized with COVID‐19, we analyzed clinical data, treatment including palliative care, and outcomes in patients with SARS‐CoV‐2 infection admitted to three hospitals in Seattle, Washington. We compared data between patients who were discharged and non‐survivors. RESULTS: Age (OR 4.67 [1.43, 15.32] ages 65‐79; OR 3.96 [1.05, 14.89] ages 80‐97), dementia (OR 5.62 [1.60, 19.74]), and transfer from a congregate living facility (OR 5.40 [2.07, 14.07]), as well hypoxemia and tachypnea (OR 7.00 [2.91, 22.41]; OR 2.78 [1.11, 6.97]) were associated with mortality. Forty‐one (41%) patients required intensive care and 22 (22%) invasive mechanical ventilation. Forty‐six (46%) patients were seen by the palliative care service, resulting in a change of resuscitation status in 54% of admitted patients. Fifty‐eight (58%) patients recovered and were discharged, 34 (34%) died, and eight (8%) remained hospitalized, of which seven ultimately survived and one died. CONCLUSIONS: Older age, dementia, and congregate living were associated with mortality. Early discussions of goals of care facilitated by an operational palliative care consult service can effectively guide goal‐concordant care in patients at high risk for mortality during a pandemic. Development of a functional palliative care consult service is an important component of pandemic planning.
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spelling pubmed-85623122021-11-08 Clinical presentation, complications, and outcomes of hospitalized COVID‐19 patients in an academic center with a centralized palliative care consult service Baker, Sarah M. Leedy, Doug J. Klafter, Jesse Abbott Zhang, Yilin Secrest, Kayla M. Osborn, Tristan R. Cheng, Richard K. Judson, Seth D. Merel, Susan E. Mikacenic, Carmen Bhatraju, Pavan K. Liles, W. Conrad Health Sci Rep Research Articles BACKGROUND AND AIMS: Palliative care is a critical component of the response of a healthcare system to a pandemic. We present risk factors associated with mortality and highlight an operational palliative care consult service in facilitating early identification of risk factors to guide goal‐concordant care and rational utilization of finite healthcare resources during a pandemic. METHODS: In this case series of 100 consecutive patients hospitalized with COVID‐19, we analyzed clinical data, treatment including palliative care, and outcomes in patients with SARS‐CoV‐2 infection admitted to three hospitals in Seattle, Washington. We compared data between patients who were discharged and non‐survivors. RESULTS: Age (OR 4.67 [1.43, 15.32] ages 65‐79; OR 3.96 [1.05, 14.89] ages 80‐97), dementia (OR 5.62 [1.60, 19.74]), and transfer from a congregate living facility (OR 5.40 [2.07, 14.07]), as well hypoxemia and tachypnea (OR 7.00 [2.91, 22.41]; OR 2.78 [1.11, 6.97]) were associated with mortality. Forty‐one (41%) patients required intensive care and 22 (22%) invasive mechanical ventilation. Forty‐six (46%) patients were seen by the palliative care service, resulting in a change of resuscitation status in 54% of admitted patients. Fifty‐eight (58%) patients recovered and were discharged, 34 (34%) died, and eight (8%) remained hospitalized, of which seven ultimately survived and one died. CONCLUSIONS: Older age, dementia, and congregate living were associated with mortality. Early discussions of goals of care facilitated by an operational palliative care consult service can effectively guide goal‐concordant care in patients at high risk for mortality during a pandemic. Development of a functional palliative care consult service is an important component of pandemic planning. John Wiley and Sons Inc. 2021-11-02 /pmc/articles/PMC8562312/ /pubmed/34754946 http://dx.doi.org/10.1002/hsr2.423 Text en © 2021 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Baker, Sarah M.
Leedy, Doug J.
Klafter, Jesse Abbott
Zhang, Yilin
Secrest, Kayla M.
Osborn, Tristan R.
Cheng, Richard K.
Judson, Seth D.
Merel, Susan E.
Mikacenic, Carmen
Bhatraju, Pavan K.
Liles, W. Conrad
Clinical presentation, complications, and outcomes of hospitalized COVID‐19 patients in an academic center with a centralized palliative care consult service
title Clinical presentation, complications, and outcomes of hospitalized COVID‐19 patients in an academic center with a centralized palliative care consult service
title_full Clinical presentation, complications, and outcomes of hospitalized COVID‐19 patients in an academic center with a centralized palliative care consult service
title_fullStr Clinical presentation, complications, and outcomes of hospitalized COVID‐19 patients in an academic center with a centralized palliative care consult service
title_full_unstemmed Clinical presentation, complications, and outcomes of hospitalized COVID‐19 patients in an academic center with a centralized palliative care consult service
title_short Clinical presentation, complications, and outcomes of hospitalized COVID‐19 patients in an academic center with a centralized palliative care consult service
title_sort clinical presentation, complications, and outcomes of hospitalized covid‐19 patients in an academic center with a centralized palliative care consult service
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562312/
https://www.ncbi.nlm.nih.gov/pubmed/34754946
http://dx.doi.org/10.1002/hsr2.423
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