Phosphorylation Regulates CIRBP Arginine Methylation, Transportin-1 Binding and Liquid-Liquid Phase Separation

Arginine-glycine(-glycine) (RG/RGG) regions are highly abundant in RNA-binding proteins and involved in numerous physiological processes. Aberrant liquid-liquid phase separation (LLPS) and stress granule (SGs) association of RG/RGG regions in the cytoplasm have been implicated in several neurodegene...

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Detalles Bibliográficos
Autores principales: Lenard, Aneta J., Hutten, Saskia, Zhou, Qishun, Usluer, Sinem, Zhang, Fangrong, Bourgeois, Benjamin M. R., Dormann, Dorothee, Madl, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562343/
https://www.ncbi.nlm.nih.gov/pubmed/34738012
http://dx.doi.org/10.3389/fmolb.2021.689687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562343/
https://www.ncbi.nlm.nih.gov/pubmed/34738012
http://dx.doi.org/10.3389/fmolb.2021.689687

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