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Delirious mania in a patient with COVID-19 pneumonia

Delirious mania (the coexistence of delirium and mania) is described in the literature but not recognised in standard nosologies. We report a woman in her late 30s, with no psychiatric history, who presented with concurrent symptoms of mania and delirium. She was diagnosed with COVID-19 pneumonia (p...

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Autores principales: Haddad, Peter M, Alabdulla, Majid, Latoo, Javed, Iqbal, Yousaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562355/
https://www.ncbi.nlm.nih.gov/pubmed/34725060
http://dx.doi.org/10.1136/bcr-2021-243816
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author Haddad, Peter M
Alabdulla, Majid
Latoo, Javed
Iqbal, Yousaf
author_facet Haddad, Peter M
Alabdulla, Majid
Latoo, Javed
Iqbal, Yousaf
author_sort Haddad, Peter M
collection PubMed
description Delirious mania (the coexistence of delirium and mania) is described in the literature but not recognised in standard nosologies. We report a woman in her late 30s, with no psychiatric history, who presented with concurrent symptoms of mania and delirium. She was diagnosed with COVID-19 pneumonia (positive reverse transcription-PCR test). There was no history of substance misuse or concurrent medical illness. CT head scan was normal as were blood investigations, other than elevated inflammatory markers. She received standard treatment for COVID-19 pneumonia and lorazepam and quetiapine to treat her neuropsychiatric symptoms. She made a full recovery after 9 days. She was apyrexial with normal oxygen saturation throughout her illness. The case shows that severe neuropsychiatric symptoms can complicate otherwise mild COVID-19 pneumonia with neuroinflammation being a possible mechanism. A diagnosis of delirious mania appears to better capture the complexity of the presentation than a diagnosis of mania or delirium alone.
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spelling pubmed-85623552021-11-15 Delirious mania in a patient with COVID-19 pneumonia Haddad, Peter M Alabdulla, Majid Latoo, Javed Iqbal, Yousaf BMJ Case Rep Case Report Delirious mania (the coexistence of delirium and mania) is described in the literature but not recognised in standard nosologies. We report a woman in her late 30s, with no psychiatric history, who presented with concurrent symptoms of mania and delirium. She was diagnosed with COVID-19 pneumonia (positive reverse transcription-PCR test). There was no history of substance misuse or concurrent medical illness. CT head scan was normal as were blood investigations, other than elevated inflammatory markers. She received standard treatment for COVID-19 pneumonia and lorazepam and quetiapine to treat her neuropsychiatric symptoms. She made a full recovery after 9 days. She was apyrexial with normal oxygen saturation throughout her illness. The case shows that severe neuropsychiatric symptoms can complicate otherwise mild COVID-19 pneumonia with neuroinflammation being a possible mechanism. A diagnosis of delirious mania appears to better capture the complexity of the presentation than a diagnosis of mania or delirium alone. BMJ Publishing Group 2021-11-01 /pmc/articles/PMC8562355/ /pubmed/34725060 http://dx.doi.org/10.1136/bcr-2021-243816 Text en © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.
spellingShingle Case Report
Haddad, Peter M
Alabdulla, Majid
Latoo, Javed
Iqbal, Yousaf
Delirious mania in a patient with COVID-19 pneumonia
title Delirious mania in a patient with COVID-19 pneumonia
title_full Delirious mania in a patient with COVID-19 pneumonia
title_fullStr Delirious mania in a patient with COVID-19 pneumonia
title_full_unstemmed Delirious mania in a patient with COVID-19 pneumonia
title_short Delirious mania in a patient with COVID-19 pneumonia
title_sort delirious mania in a patient with covid-19 pneumonia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562355/
https://www.ncbi.nlm.nih.gov/pubmed/34725060
http://dx.doi.org/10.1136/bcr-2021-243816
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