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QSAR analysis of pyrimidine derivatives as VEGFR-2 receptor inhibitors to inhibit cancer using multiple linear regression and artificial neural network

BACKGROUND AND PURPOSE: In this study, the pharmacological activity of 33 compounds of furopyrimidine and thienopyrimidine as vascular endothelial growth factor receptor 2 (VEGFR-2) inhibitors to inhibit cancer was investigated. The most important angiogenesis inducer is VEGF endothelial growth fact...

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Detalles Bibliográficos
Autores principales:	Masoomi Sefiddashti, Fariba, Asadpour, Saeid, Haddadi, Hedayat, Ghanavati Nasab, Shima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562410/ https://www.ncbi.nlm.nih.gov/pubmed/34760008 http://dx.doi.org/10.4103/1735-5362.327506

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