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Contrasting role of NLRP12 in autoinflammation: evidence from a case report and mouse models

OBJECTIVE: To explore at the molecular level the phenotype of a patient suffering an autoinflammatory syndrome which was diagnosed as familial cold autoinflammatory syndrome type 2 (FCAS-2). To explore the functions of Nlrp12 in inflammation using mouse models. METHODS: Whole exome sequencing and Nl...

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Detalles Bibliográficos
Autores principales:	Lévy, Dan, Mariotte, Alexandre, DeCauwer, Aurore, Macquin, Cecile, Pichot, Angélique, Molitor, Anne, Maurier, Francois, Meyer, Alain, Carapito, Raphael, Georgel, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Autoinflammatory Disorders
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562517/ https://www.ncbi.nlm.nih.gov/pubmed/34725261 http://dx.doi.org/10.1136/rmdopen-2021-001824

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